Temporal appearance of plasmid-mediated quinolone resistance genes.

نویسندگان

  • George A Jacoby
  • Nancy Gacharna
  • Todd A Black
  • George H Miller
  • David C Hooper
چکیده

One hundred fifty AAC(6')-Ib-positive gram-negative isolates collected between 1981 and 1991 were examined by PCR for the presence of the aac(6')-Ib-cr variant and other plasmid-mediated quinolone resistance (PMQR) genes. None had the aac(6')-Ib-cr variant, qnrA, qnrS, qnrC, or qepA, but two strains collected in 1988 had qnrB alleles, making these the earliest known PMQR genes.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 53 4  شماره 

صفحات  -

تاریخ انتشار 2009